Study of the phenolic compounds, biostimulation and biological activities of Ludwigia grandiflora (Michx.) Greuter& Burdet, 1987
| dc.contributor.author | Chebel, Roukaya | |
| dc.contributor.author | Doghmane ,Lamisse Nourhane | |
| dc.contributor.author | Dr. B. AOUZEL | |
| dc.date.accessioned | 2025-12-04T08:31:47Z | |
| dc.date.available | 2025-12-04T08:31:47Z | |
| dc.date.issued | 2025 | |
| dc.description.abstract | Ludwigia grandiflora, a member of the Onagraceae family, has garnered significant attention for its phytochemical richness and therapeutic potential. This study investigates the bioactive compounds present in the ethanolic extract of L. grandiflora (Michx.) Greuter & Burdet, 1987, focusing on its antioxidant, antimicrobial, and anti-inflammatory activities. Using a comprehensive set of in vitro assays, including DPPH, ABTS, and total antioxidant activity tests, the extract demonstrated potent free radical scavenging activity and high antioxidant capacity, with an IC₅₀ of 0.495 mg/mL for DPPH. Antimicrobial evaluation revealed significant inhibitory effects on both Gram-negative and Gram-positive bacteria, including Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus, with the most prominent antibacterial activity observed against S. aureus. Additionally, the extract exhibited substantial anti-inflammatory effects, as evidenced by its ability to inhibit protein denaturation in both human and bovine serum albumin assays, showing up to 62.39% inhibition at the highest concentration.Phytochemical analysis revealed high concentrations of phenolic compounds, flavonoids, and tannins, which are likely contributors to the observed bioactivities. Chlorophyll content was also assessed, revealing high levels of chlorophyll a (5.5370 mg/L), chlorophyll b (3.2571 mg/L), and total chlorophyll (8.7941 mg/L), indicating a strong presence of photosynthetic pigments. Furthermore, biostimulation assays showed that low concentrations of the extract significantly enhanced seed germination, with the highest germination rate observed at 0.003125 (1.23 cm), followed by 0.0125 (0.601 cm), both outperforming the control group.These results suggest that L. grandiflora holds significant promise as a source of natural antioxidants, antimicrobial agents, anti-inflammatory substances, and plant biostimulants, offering potential for therapeutic applications in traditional medicine, pharmaceutical development, and sustainable agriculture. | |
| dc.identifier.uri | http://dspace.univ-skikda.dz:4000/handle/123456789/5536 | |
| dc.language.iso | en | |
| dc.publisher | Faculty of Science | |
| dc.title | Study of the phenolic compounds, biostimulation and biological activities of Ludwigia grandiflora (Michx.) Greuter& Burdet, 1987 | |
| dc.title.alternative | Pharmaceutical Chemistry | |
| dc.type | Mémoire de Master |