Simulation de la couche sensible ZnO pour la détection du glucose.
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Date
2026-07-20
Journal Title
Journal ISSN
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Publisher
Université 20 août 1955 Skikda
Abstract
This thesis focuses on the modeling and simulation of an electrochemical biosensor based on
zinc oxide (ZnO), a semiconductor material widely recognized for its chemical stability,
biocompatibility, and excellent electrochemical properties. The main objective of this work is
to develop a numerical model to investigate the electrochemical behavior of the biosensor and
evaluate its performance for glucose detection. The simulations were carried out using
COMSOL Multiphysics based on the finite element method, taking into account species
transport, electrochemical reactions, and charge transfer at the electrode/solution interface. The
biosensor performance was evaluated through several electrochemical characterization
techniques, including cyclic voltammetry, electrochemical impedance spectroscopy (Nyquist
plots), and the variation of current density as a function of glucose concentration. The obtained
results demonstrate an improvement in the electrochemical response with increasing glucose
concentration, highlighting the effectiveness of the ZnO-sensitive layer. These findings confirm
the potential of numerical modeling and simulation for the design and optimization of highperformance electrochemical biosensors for biomedical applications.